Malaria Recommendations for HIV-Positive People Traveling to Malaria Risk Areas
HIV-positive people are at higher risk for malaria because of their weakened immune systems and should be sure to follow the standard mosquito precautions recommended for all travelers to malaria risk areas
Malaria chemoprophylaxis for HIV-positive travelers(Use of anti-malarial drugs to prevent the development of malaria) follows the same guidelines as those for HIV-negative travelers, although potential drug interactions between antimalarials and antiretroviral drugs should be considered.
If travelers, regardless of their HIV status, should experience symptoms of malaria, they should seek help right away and, if diagnosed with malaria, be treated with a highly effective antimalarial drug. The importance of precautions against mosquito bites should be emphasized.
Yellow fever
Proof of vaccination is required for all travellers coming from countries where yellow fever occurs, including transit through such countries. The international yellow fever vaccination certificate becomes valid 10 days after vaccination and remains valid for a period of 10 years.
The fact that a country has no mandatory requirement for vaccination does not imply that there is no risk of yellow fever infection
Live Vaccines
- Poilio (oral)
- Typhoid (oral)
- Yellow Fever
Inactivated Vaccines (not Live)
- Meningitis
- Hepatitis A
- Hepatitis B
- Typhoid
- Tetanus
- Diphtheria
- Rabies
- Encephalitis
Vaccine [Indication] Common use
- Anthrax [RS] Occupational
- Cholera WC/rBS [RS] Travel
- Hepatitis A [RS] Risk groups
- Hepatitis B [R]
- Haemophilus influenzae [RS] Risk groups
- Influenza-parenteral [R] Indications are strengthened in the presence of additional risk factors
- Japanese encephalitis [RS] Travel
- Meningococcus (MenC) [RS] Risk groups
- Meningococcus (ACWY) [RS] Travel
- Pneumococcus (PPV23) [R] Indications are strengthened in the presence of additional risk factors
- Rabies [RS] Travel
- Tetanus-diphtheria-parenteral poliomyelitis (Td/IPV)
- RS Uncertain vaccination status or travel Tick-borne encephalitis [RS] Travel
- Typhoid (ViCPS) [RS]
R = recommended in all
RS = recommended in selected
Live vaccines for HIV travellers
Live vaccines that may be indicated in HIV-infected persons, but should not be used if the CD4 count is o200 cells/mL
Vaccine
- Measles ,Mumps, Rubella (MMR)
- Varicella
- Yellow fever
Live vaccines contraindicated in all HIV-infected adults regardless of CD4 cell count
Vaccine
- Cholera (CVD103-HgR)
- Influenza (intranasal) Also contraindicated in close contacts
- Oral poliomyelitis (OPV) Also contraindicated in close contacts
- Typhoid (Ty21a)
- Tuberculosis (BCG)
- Smallpox (Vaccinia) Exceptions apply)
Vaccines recommended for HIV-infected adults found to be susceptible upon serological screening
(CD4 count) (cells/lL) Vaccine
- Hepatitis B
- Any Measles, mumps,rubella (MMR)
- 4200 All measles IgG seronegative persons; rubella IgG seronegative women of child-bearing age Varicella 4400 Also consider if 4200 All VZV IgG seronegative persons Table 5
Vaccines recommended for HIV-infected adults who have missed routine childhood vaccinations or have uncertain vaccination history
Vaccine Group CD4 count (cells/lL) Comments Tetanus-diphtheria/ parenteral poliomyelitis (Td/IPV) All Any Complete a five-dose course regardless of the interval since the last dose and the type of vaccine received previously Meningococcus-MenC Adults o25 years
Vaccines for travel-related indications
(CD4 count)(cells/lL)Vaccine Indication
- Meningococcus (ACWY) [M] Recommended for travel to endemic or epidemic areas; mandatory for all Hajj and Umrah pilgrims; follow standard guidelines
- (Any) Yellow fever [M] Consider if at true risk of infection
- (4200) Hepatitis B [R] If prolonged travel
- Any Measles, mumps, rubella (MMR) [R] If measles IgG seronegative
- (4200) Tetanus-diphtheria/ parenteral poliomyelitis (Td/IPV) [R] Every 10 years
- (Any) Cholera (WC/rBS) [S] Follow standard guidelines
- (Any) Hepatitis A [S] Follow standard guidelines
- (Any) Japanese encephalitis [S] Follow standard guidelines
- (Any) Tick-borne encephalitis [S] Follow standard guidelines
- (Any) Typhoid (ViCPS) S Low threshold for offering vaccination
- (Any) Rabies S Low threshold for offering vaccination
It is recognized that the responsibility for providing the recommended immunizations and for meeting the associated costs remains an unresolved issue. It is currently envisaged that the HIV specialist should provide overall guidance on vaccine use and enlist the help of primary care physicians for vaccine administration where feasible. As is the case with HIV-negative travellers, HIV-infected persons should be advised that they will be expected to meet the cost of vaccines required for travel. Finally, while it is hoped that these guidelines will inform immunization practices widely, they are intended primarily for HIV infected adults in the UK
M, Mandatory for travel to selected countries. These vaccines are legal requirements for travel to some countries. Failure to obtain the vaccine could result in non-entry/quarantine in destination. Waiver documents may not be accepted by some countries.
R, Recommended
S, Selective use for travellers to risk areas. Recommendations for these vaccines depend on the countries of destination, the epidemic situation at the time of travel, the purpose of travel, the intended length of stay and the health status of the traveller. Because recommendations will change from time to time, it is prudent to access up-to-date health information for specific destinations.